RIFAMINE-400

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Description

RIFAMINE-400 is a powerful gut-targeting antibiotic combining the broad-spectrum antibiotic rifaximin 400 mg. Rifaximin is a topical, systemic-action, broad-spectrum antibiotic, designed for use within the GI tract with high local concentration and low systemic absorption, making it a common choice among gastroenterologists and physicians for the treatment of travellers’ diarrhoea, hepatic encephalopathy, IBS-D and other GI bacterial overgrowth diseases.

Produced at WHO-GMP-approved plants and packed in handy 10X10 blister forms, the trust for safe, powerful and result-oriented gastro care is offered by Senen Biotech to Doctors, hospitals, and Pharmacies pan India.

Uses and Indications

Common indications for RIFAMINE-400 Tablets: Prescribed by Gastroenterologists, Hepatologists & General physicians for: 

  • Travellers’ diarrhoea of non-invasive E. Coli
  • Prevent recurrence of overt Hepatic encephalopathy.
  • Irritable Bowel Syndrome with Diarrhoea(IBS-D)in adults
  • Small Intestinal Bacterial Overgrowth (SIBO)
  • Hepatic encephalopathy adjunctive to therapy of lactulose
  • Bacterial diarrhoea & GI infections of bacterial origin
  • Adjunctive treatment in diverticular disease (with advice of physician)

How Rifaximin Tablets 400 mg Works

Rifaximin Tablets 400 mg stops bacterial RNA production, mostly because it binds to the beta subunit of bacterial DNA-dependent RNA polymerase. So, it blocks bacterial transcription in a pretty direct way. Also, it is poorly absorbed from the gastrointestinal tract, so it doesn’t really go all over the body. Instead, it stays mostly in the gut lumen, which lets it build high local antibacterial concentrations right where the problem is, rather than causing systemic side effects like some absorbable antibiotics do. This sort of targeted approach is why rifaximin shows activity against a pretty wide mix of gram-positive and gram-negative aerobic as well as anaerobic bacteria, the ones linked with GI infections, and even ammonia-producing bacteria involved in hepatic encephalopathy.

Dosage and Administration

Rifaximin Tablets 400 mg are intended for oral use only and must be administered strictly under medical supervision. The dose, frequency, and duration of therapy should be determined by a registered medical practitioner based on the indication being treated, the patient’s clinical condition, and response to therapy. The tablet may be taken with or without food, as advised. Self-medication without proper diagnosis is not recommended.

Side Effects

RIFAMINE-400 is generally well tolerated due to its minimal systemic absorption. However, some patients may experience mild and usually transient effects, including:

  • Nausea or mild abdominal discomfort
  • Flatulence or bloating
  • Headache or mild dizziness
  • Fatigue or peripheral oedema (more commonly reported in hepatic encephalopathy patients)
  • Loose motions or urge to defecate
  • Rarely, an allergic skin reaction such as rash or itching

Patients experiencing persistent or severe side effects, including signs of an allergic reaction, should discontinue use and consult their physician promptly.

Precautions and Warnings

  • This product is for use by adults only under the supervision of a qualified healthcare professional.
  • Tell your healthcare provider if you are allergic to rifaximin, rifamycin antibiotics, or any of the other ingredients in this tablet.
  • Patients with severe hepatic impairment (Child-Pugh Class C) should be use with caution because their systemic exposure is increased.
  • Tell your doctor if you are pregnant or breastfeeding, or if you have a history of liver disease.
  • See a doctor right away if your diarrhoea persists or is worsened, if it comes with a fever and with blood in the stool. This indicates something else is causing the problem.
  • Use with caution in patients who have C. Difficile-associated diarrhoea.
  • Do not use this medication together with any other antibiotic unless ordered by your doctor.
  • Do not use more of the drug, or take it for longer, than prescribed.
  • Keep this drug out of the reach of children.
  • Store the drug in a cool, dry place, away from heat and direct light. Consult the packaging instructions.

Storage Instructions

Store RIFAMINE-400 Tablets below 25°C, in a dry place, protected from light and moisture. Keep the tablets in their original blister packaging until ready for use, and keep out of reach of children and pets.

Note: The above content is only for informational purposes and does not guarantee anything. Therefore, must inform your doctor before taking this medication. 

PCD Pharma Franchise for Rifaximin Tablets 400 mg – Senen Biotech

Pharma professionals, distributors and medical representatives across India, come and grab this incredible PCD Pharma Franchise and Monopoly Distribution rights of RIFAMINE-400 Tablets. We bring you our rich portfolio of best-selling gastro, antibiotic and general range products backed by robust manufacturing practices, competitive profit margins, and an aggressive marketing strategy.

What makes Senen Biotech the best partner for the PCD Pharma Franchise of RIFAMINE-400 Tablets?

  • PCD Pharma Franchise with Exclusive Monopoly rights of RIFAMINE-400 Tablets at the district/state level
  • Highly Profitable Margins and Competing Prices across all ranges of gastro and antibiotic formulations.
  • Comprehensive Product List in tablet, capsule, Syrup and Injectable dosage forms to provide you excellent product choice for cross-selling.
  • Complementary promotional inputs like VIs, MR Bags, Sample Covers, Prescription pads, Reminder cards and Literature.
  • On-time delivery and Order fulfilment with an efficient logistics network throughout India.
  • Dedicated Franchise Management Team for smooth onboarding and to offer continued business support.

Additional information

Packing

10X10